Recruitment
Sites opened
40 sites randomised participants into the PROFILE trial.
The trial has now closed to recruitment and follow up has been completed (Feb 2023). Results fo the trial will soon be made available.
Participants randomised
| Site Name | Total | Step Up | Top Down |
|---|---|---|---|
| Addenbrooke's Hospital, Dr Nurulamin Noor | 81 | 45 | 36 |
| St Georges Hospital, Dr Kamal Patel | 65 | 27 | 38 |
| Barts and Royal London Hospital, Dr Klaartje Kok | 20 | 11 | 9 |
| Royal Liverpool Hospital, Prof Chris Probert | 17 | 9 | 8 |
| Western General Hospital, Dr Shahida Din | 17 | 9 | 8 |
| Royal Hampshire County Hospital, Dr John Gordon | 16 | 6 | 10 |
| Russells Hall Hospital, Dr Shanika de Silva | 15 | 7 | 8 |
| Royal Sussex County Hospital, Dr Melissa Smith | 11 | 4 | 7 |
| Kings College Hospital, Dr Alexandra Kent | 9 | 7 | 2 |
| Luton & Dunstable University Hospital, Dr Matthew Johnson | 9 | 4 | 5 |
| Basingstoke and North Hampshire Hospital, Dr Rebecca Saich | 9 | 5 | 4 |
| Queen Elizabeth, King's Lynn, Dr Alan Wiles | 8 | 6 | 2 |
| University Hospital of Wales, Dr Dharmaraj Durai | 8 | 5 | 3 |
| Royal Devon and Exeter Hospital, Dr Tariq Ahmad | 8 | 2 | 6 |
| Queen's Medical Centre, Nottingham, Dr Gordon Moran | 8 | 5 | 3 |
| Epsom General Hospital, Dr Pritash Patel | 7 | 4 | 3 |
| Queen Elizabeth Hospital Birmingham, Dr Rachel Cooney | 6 | 3 | 3 |
| West Suffolk Hospital, Dr Dan Sharpstone | 6 | 3 | 3 |
| Guy's and St Thomas' Hospital, Dr Peter Irving | 6 | 4 | 2 |
| James Paget Hospital, Dr Paul Banim | 6 | 3 | 3 |
| Ninewells Hospital, Dr Craig Mowat | 5 | 1 | 4 |
| St Mary's Hospital, Dr Horace Williams | 5 | 1 | 4 |
| Royal Glamorgan, Dr James Berrill | 5 | 3 | 2 |
| Royal Bournemouth Hospital, Dr Sean Weaver | 4 | 3 | 1 |
| New Cross Hospital, Dr Matthew Brookes | 4 | 2 | 2 |
| Blackpool Victoria Hospital, Dr Rhys Butcher | 4 | 1 | 3 |
| Musgrove Park Hospital, Dr Emma Wesley | 3 | 3 | 0 |
| Watford Hospital, Dr Rakesh Chaudhary | 3 | 2 | 1 |
| Darlington Memorial Hospital, Dr Anjan Dhar | 3 | 1 | 2 |
| James Cook Hospital, Dr Arvind Ramadas | 3 | 1 | 2 |
| Bedford Hospital, Dr Babur Javaid | 2 | 1 | 1 |
| Kingston Hospital, Dr Rishi Goel | 2 | 2 | 0 |
| New Victoria Hospital, Dr Rob Boulton-Jones | 2 | 0 | 2 |
| Royal Victoria Infirmary, Dr Ally Speight | 2 | 1 | 1 |
| St Mark's Hospital, Prof Ailsa Hart | 2 | 0 | 2 |
| Torbay Hospital, Dr Sam Powles | 2 | 0 | 2 |
| Royal Shrewsbury Hospital, Dr Jeff Butterworth | 2 | 2 | 0 |
| Wythenshawe Hospital, Dr Paul Knight | 2 | 1 | 1 |
| Worthing Hospital, Dr Andy Li | 1 | 0 | 1 |
| Royal Derby Hospital, Dr Andy Cole | 1 | 1 | 0 |
Recruitment Progress
Page last updated: 30/10/2023